Surinam cherry leaves exhibit notable anti-inflammatory, antioxidant, and antibacterial properties

A recent study has found that the leaves of the Eugenia uniflora Linn, commonly known as the Surinam cherry, is a potent antioxidant, and it possessed astringent, antibacterial, and anti-inflammatory properties. These findings, published in BMC Complementary and Alternative Medicine, were the result of multiple assays to determine its phytochemical properties and evaluate its various health benefits.

• Researchers utilized the crude extract (CE) of E. uniflora in aqueous- (AqF) and ethyl acetate- (EAF) treated fractions.
• To determine its phytochemical content, both fractions underwent chromatographic analysis, while an agar dilution assay evaluated antibacterial activity based on minimum inhibitory concentrations (MICs).
• Peritonitis-induced mouse models were given 50, 100, and 200 mg of CE per kilogram of body weight (mg/kg), AqF, and EAF.
• Biomarkers including total glutathione and malondialdehyde (MDA), IL-1? and TNF-? levels were measured using a UV/VIS analysis. Researchers also used an abdominal writhing model and a hot plate test to determine antinociceptive ability.
• The findings revealed that E. uniflora contained gallic acid, ellagic acid, and myricitrin; CE and fractions contained differing levels, respectively.
• Researchers found that CE had the lowest MIC against MRSA strain, and both CE and AqF reduced leukocyte and migration and MPO activity. Moreover, AqF reduced biomarkers for inflammation.

Researchers concluded that both CE and fractions of E. uniflora leaves contained antibacterial, anti-inflammatory, antioxidant, and analgesic activity.

Find the full text of the study at this link.

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Journal Reference:

Falcão TR, Araújo AAD, Soares LAL, Ramos RTDM, Bezerra ICF, Ferreira MRA, Neto MADS, Melo MCN, Araújo RFD, Guerra ACVDA, et al. CRUDE EXTRACT AND FRACTIONS FROM EUGENIA UNIFLORA LINN LEAVES SHOWED ANTI-INFLAMMATORY, ANTIOXIDANT, AND ANTIBACTERIAL ACTIVITIES. BMC Complementary and Alternative Medicine. 9 March 2018;18(84). DOI: 10.1186/s12906-018-2144-6